Title :
Dynamic evaluation of [18F]-FDG uptake in the rat brain by microPET imaging
Author :
Chen, Y.Y. ; Chien, C.N. ; Lee, T.W. ; Fu, Y.K. ; Kuo, T.S. ; Jaw, F.-S.
Author_Institution :
Inst. of Electr. Eng., Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
This study aims to acquire the functional image of the rat brain, small animal positron emission tomography (microPET) with high resolution and sensitivity is adopted to assess the metabolic activity corresponding to the neuronal activity induced by the electrical stimulation of the rat tail using [18F] fluorodeoxyglucose (FDG) as the radiotracer. The microPET imaging technology can provide anatomical and functional information on neuronal activity used to analyze responses in pathway sequence relationships between the thalamus and the cerebral cortex.
Keywords :
bioelectric phenomena; brain; neurophysiology; positron emission tomography; radioactive tracers; [/sup 18/F]-FDG uptake; cerebral cortex; electrical stimulation; fluorodeoxyglucose; metabolic activity; microPET imaging; neuronal activity; radiotracer; rat brain; rat tail; small animal positron emission tomography; thalamus; Animals; Cerebral cortex; Electrical stimulation; High-resolution imaging; Image analysis; Image resolution; Image sequence analysis; Information analysis; Positron emission tomography; Tail; Electrical stimulation; fluorodeoxyglucose; microPET;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1404240
