DocumentCode
2745645
Title
A model of the respiratory central pattern generator
Author
Amini, Behrang ; Bidani, Akhil ; Zwischenberger, Joseph B. ; Clark, John W., Jr.
Author_Institution
Dept. of Neurobiol. & Anatomy, Texas Univ., Houston, TX, USA
Volume
2
fYear
2004
fDate
1-5 Sept. 2004
Firstpage
4580
Lastpage
4583
Abstract
We have developed a model of the mammalian respiratory central pattern generator (rCPG) to mimic the salient characteristics of its constituent medullary neurons. This model was designed as a network of Hodgkin-Huxley type medullary neurons under the hypothesis that synaptic and network effects predominate over ionic influences in determining the pattern of firing seen in individual neurons. After obtaining satisfactory mimicry of these patterns we validated the model to a different set of data in order to examine its robustness in the face of transient perturbations.
Keywords
bioelectric phenomena; neurophysiology; physiological models; pneumodynamics; Hodgkin-Huxley type medullary neurons; mammalian respiratory central pattern generator; medullary neurons; network effects; neuron firing; respiratory central pattern generator; synaptic effects; Anatomy; Biological system modeling; Biology computing; Biomedical engineering; Computational biology; Consortia; Frequency; Lungs; Nerve fibers; Neurons;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location
San Francisco, CA
Print_ISBN
0-7803-8439-3
Type
conf
DOI
10.1109/IEMBS.2004.1404270
Filename
1404270
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