Title :
An Improved Simulated Annealing Algorithm and its Application to Protein Structure Prediction
Author :
Guo, Chonghui ; Zhu, Ping ; Tang, Huanwen ; Lu, Mingyu
Author_Institution :
Dept. of Appl. Math., Dalian Univ. of Technol.
Abstract :
Simulated annealing is a heuristic global optimization algorithm, which has been successfully applied to many difficult optimization problems. This paper proposes an improved simulated annealing algorithm to search the ground state of HP off-lattice model for protein folding. Numerical results show that the improved simulated annealing algorithm is feasible and effective to search the ground state of HP off-lattice model
Keywords :
biology; proteins; search problems; simulated annealing; HP off-lattice model; global optimization algorithm; protein folding; protein structure prediction; simulated annealing; Application software; Computational modeling; Computer science; Heuristic algorithms; Intelligent control; Mathematics; Predictive models; Proteins; Simulated annealing; Stationary state; HP off-lattice model; protein structure prediction; simulated annealing;
Conference_Titel :
Intelligent Control and Automation, 2006. WCICA 2006. The Sixth World Congress on
Conference_Location :
Dalian
Print_ISBN :
1-4244-0332-4
DOI :
10.1109/WCICA.2006.1713817
