Title :
Development and characterization of a hexamodal imaging nanoparticle
Author :
Rieffel, James ; Feng Chen ; Jeesu Kim ; Guanying Chen ; Wei Shao ; Shuai Shao ; Chitgupi, Upendra ; Hernandez, Reinier ; Graves, Stephen A. ; Nickles, Robert J. ; Prasad, Paras N. ; Chulhong Kim ; Weibo Cai ; Lovell, Jonathan F.
Author_Institution :
Dept. of Biomed. Eng., Univ. at Buffalo, New York, NY, USA
Abstract :
Porphyrin-phospholipids are used to coat upconversion nanoparticles in order to generate a new biocompatible material. The nanoparticles are characterized in vitro and in vivo for imaging via fluorescence, upconversion, positron emission tomography, computed tomography.
Keywords :
acoustic tomography; bioluminescence; biomedical optical imaging; fluorescence; lipid bilayers; nanocomposites; nanofabrication; nanomedicine; nanoparticles; optical tomography; positron emission tomography; Cerenkov luminescence; biocompatible material; computed tomography; fluorescence; hexamodal imaging nanoparticle; photoacoustic tomography; porphyrin-phospholipids; positron emission tomography; upconversion nanoparticle coating; Biomedical imaging; Computed tomography; In vivo; Lymph nodes; Nanoparticles; Positron emission tomography;
Conference_Titel :
Biomedical Engineering Conference (NEBEC), 2015 41st Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-4799-8358-2
DOI :
10.1109/NEBEC.2015.7117194
