Title :
Non-invasive assessment of tumor proliferation using triple quantum filtered 23Na MRI: technical challenges and solutions
Author :
Boada, F.E. ; Tanase, C. ; Davis, D. ; Walter, K. ; Torres-Trejo, A. ; Couce, M. ; Hamilton, R. ; Kondziolka, D. ; Bartynski, W. ; Lieberman, F.
Author_Institution :
Pittsburgh Univ., PA, USA
Abstract :
We address the development of triple-quantum-filtered sodium MRI as a non-invasive surrogate measure for cell proliferation in brain tumors. We demonstrate that through careful consideration of the theoretical description of the signal, triple-quantum-filtered sodium images of adequate signal-to-noise ratio (SNR) can be acquired in clinically acceptable imaging times.
Keywords :
biomedical MRI; brain; cancer; cellular biophysics; medical image processing; tumours; Na; brain tumors; cell proliferation; technical challenges; triple quantum filtered /sup 23/Na MRI; tumor proliferation; Biopsy; Electric breakdown; In vivo; Magnetic resonance imaging; Neoplasms; Nuclear magnetic resonance; Nuclear measurements; Optical imaging; Optical microscopy; Signal to noise ratio;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1404464
