Title :
Patterning to influence in vitro neuronal interfaces
Author :
Wheeler, Bruce C. ; Nam, Yoonkey ; Brewer, Gregory J.
Author_Institution :
Dept. of Bioeng., Illinois Univ., Urbana, IL, USA
Abstract :
Microlithographic techniques applied to control surface chemistry can be used to guide neurons to surface electrodes in in vitro culture. Here we report on the effectiveness of these techniques as measured by the likelihood of recording electrical signals and detecting propagation of network activity.
Keywords :
bioelectric phenomena; cellular biophysics; lithography; microelectrodes; neurophysiology; cell patterning; electrical signals; in vitro culture; in vitro neuronal interfaces; microlithographic techniques; network activity; neurons; surface electrodes; Chemistry; Electrodes; Immune system; In vitro; Microelectrodes; Neurons; Nitrogen; Page description languages; Proteins; Resists; Neuronal network; cell patterning; hippocampal neurons; micro-contact printing; microelectrode array; multichannel recording; self-assembled monolayer;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1404490
