Title :
Monitoring of the aggregation phase of erythrocyte sedimentation rate by impedance method on micrometric scale
Author :
Tvarozek, Vladimir ; Krausko, Gabriel ; Zahorec, Roman ; Novotny, Ivan ; Rehacek, Vlastimil
Author_Institution :
Dept. of Microelectron., Slovak Acad. of Sci., Bratislava, Slovakia
Abstract :
The monitoring of the early stage of red blood cells sedimentation by an impedance method using a thin-film interdigitated array of microelectrodes (IDAE) is described. Time dependences of impedance |Z| exhibit maxima which are shifted to the shorter time period for cancer blood samples in comparison with inflammatory ones. Also the impedance rates (time derivate of impedance |Z|) were higher in cancer samples of blood. The sensitivity of this method was getting greater with both the decrease of the IDAE characteristic dimensions from 400 □m down to 5 □m and an increase of temperature from 18°C up to 37°C
Keywords :
aggregation; bioelectric phenomena; cellular transport; electric impedance measurement; patient monitoring; sedimentation; 18 C; 37 C; aggregation phase monitoring; cancer samples; characteristic dimensions; erythrocyte sedimentation rate; impedance time dependence; micrometric scale; red blood sedimentation early stage; temperature increase; thin-film interdigitated microelectrodes array; Cancer; Diseases; Gold; Impedance measurement; Microelectrodes; Monitoring; Paramagnetic resonance; Red blood cells; Sputtering; Transistors;
Conference_Titel :
Microtechnologies in Medicine and Biology, 1st Annual International, Conference On. 2000
Conference_Location :
Lyon
Print_ISBN :
0-7803-6603-4
DOI :
10.1109/MMB.2000.893811
