Title :
Modeling Biological Pathways: An Object-Oriented like Methodology Based on Mean Field Analysis
Author :
Francesca, Cordero ; Daniele, Manini ; Marco, Gribaudo
Author_Institution :
Dept. of Clinical & Biol. Sci., Univ. of Torino, Turin, Italy
Abstract :
In this paper we propose an object-oriented methodology based on mean field analysis that can be used to describe in an intuitive manner the behavior of systems composed by a large number of interacting objects. For instance, this technique is well suited to study complex biopathways. We apply this approach to model the lac operon gene regulatory mechanism and glycolysis pathway. Numerical results obtained from the analysis of the model are presented.
Keywords :
biology computing; genetics; object-oriented programming; biological pathways; complex biopathways; glycolysis pathway; lac operon gene regulatory mechanism; mean field analysis; object-oriented like methodology; Application software; Biological system modeling; Biological systems; Biology computing; Character generation; Computer applications; Computer science; Object oriented modeling; Switches; Systems biology; Biological Pathways; Mean Field Analysis;
Conference_Titel :
Advanced Engineering Computing and Applications in Sciences, 2009. ADVCOMP '09. Third International Conference on
Conference_Location :
Sliema
Print_ISBN :
978-1-4244-5082-4
Electronic_ISBN :
978-0-7695-3829-7
DOI :
10.1109/ADVCOMP.2009.25