Title :
Ultrathin parylene-C semipermeable membranes for biomedical applications
Author :
Lu, Bo ; Liu, Zhao ; Tai, Yu-Chong
Author_Institution :
California Inst. of Technol., Pasadena, CA, USA
Abstract :
We report here an in-depth study of the permeability of ultrathin parylene-C (0.15∓0.80 μm thick) by measuring the diffusion coefficients of FITC-dextran molecules with different molecular weights (MW). As a validation, we have successfully demonstrated the application of the ultrathin semipermeable membranes in perfusion cancer cell culture. The results show that, with a combined biocompatibility and good permeability, ultrathin parylene-C can be a promising semipermeable membrane material for biomedical applications.
Keywords :
diffusion; mechanical properties; membranes; molecular weight; permeability; biomedical applications; diffusion coefficients; molecular weights; ultrathin parylene-C semipermeable membranes; Biomedical measurements; Biomembranes; Cancer; Films; Permeability; Permeability measurement; Silicon;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2011 IEEE 24th International Conference on
Conference_Location :
Cancun
Print_ISBN :
978-1-4244-9632-7
DOI :
10.1109/MEMSYS.2011.5734472
