• DocumentCode
    278493
  • Title

    An evanescent fluorescence immunosensor based on K+ and Na+-exchanged patterned optical waveguides in glass

  • Author

    Zhou, Y. ; Magill, J.V. ; Cushley, W. ; De La Rue, R.M. ; Laybourn, P.J.R.

  • Author_Institution
    Dept. of Electron. & Electr. Eng., Glasgow Univ., UK
  • fYear
    1991
  • fDate
    33403
  • Abstract
    The authors describe, the successful fabrication of K+ and Na+-exchanged patterned waveguides and their application to wash-free immunoassays using evanescent excitation of fluorescence. Experimental results show that the specific binding of a fluorescently labelled antibody to its appropriate antigen could be resolved at the concentration level of 1 μg/ml
  • Keywords
    biological techniques and instruments; biosensors; fluorescence; ion exchange; optical glass; optical waveguides; optical workshop techniques; spectrochemical analysis; K+ ion exchange; Na+ ion exchange; antigen; evanescent fluorescence immunosensor; fabrication; fluorescently labelled antibody; glass waveguides; ion exchanged waveguides; patterned optical waveguides; specific binding; wash-free immunoassays;
  • fLanguage
    English
  • Publisher
    iet
  • Conference_Titel
    Optical Techniques and Biomedical Applications, IEE Colloquium on
  • Conference_Location
    London
  • Type

    conf

  • Filename
    181803