Title :
Highly integrated oral drug delivery system with valve based on Electro-Active-Polymer
Author :
Goettsche, T. ; Schumacher, A. ; Kohnle, J. ; Messner, S. ; Zengerle, R.
Author_Institution :
HSG-IMIT, Villingen-Schwenningen
Abstract :
We present a highly integrated system for controlled oral drug delivery to be implanted into the human denture and we discuss two key-subsystems: an osmotic pump and a normally-closed microvalve based on Electro-Active Polymers (EAP). The pump generates a hydrostatic pressure of up to 600 kPa. The valve controls a flow up to 0.9 mul/min. The complete drug delivery system is operated using 2 button cells of 1,5 V each.
Keywords :
drugs; polymers; electroactive polymer; microvalve; oral drug delivery system; osmotic pump; Biomembranes; Control systems; Drug delivery; Microvalves; Polymers; Pressure control; Reservoirs; Solids; Surgery; Valves;
Conference_Titel :
Micro Electro Mechanical Systems, 2007. MEMS. IEEE 20th International Conference on
Conference_Location :
Hyogo
Print_ISBN :
978-1-4244-095-5
Electronic_ISBN :
1084-6999
DOI :
10.1109/MEMSYS.2007.4433071
