Title :
A pilot study evaluating pulmonary nodule marking methods
Author :
Biancardi, A.M. ; Reeves, A.P. ; Yankelevitz, D.F. ; Ghiorghiu, D. ; Scott, M. ; Mann, H.
Author_Institution :
Sch. of Electr. & Comput. Eng., Cornell Univ., Ithaca, NY, USA
fDate :
June 28 2009-July 1 2009
Abstract :
Assessing the precision in the estimation of lesion dimensions is a prerequisite for the determination of growth rates and response to therapy both in clinical practice and research. An initial study was designed and performed to evaluate three different marking methods: uni-dimensional (maximum diameter of nodule in-axial plane), manual volumetric and a computer assisted mark-up (CAM) method. The CAM method has a good level of agreement with the manual method. Additionally, the CAM method is more repeatable than both the manual volumetric and uni-dimensional measures (CAM 95% Limits of Agreement (LoA):[-15.8, 21.2], manual 95% LoA [-23.4, 31.8], uni-dimensional 95% LoA [-43.8, 80.2]) so this study supports the expectation that more reproducible measurements can be made by using a computer assisted method compared to standard manual methods.
Keywords :
biology computing; biomedical measurement; cancer; computer aided analysis; lung; computer assisted mark-up method; lesion dimensions; manual volumetric method; pulmonary nodule marking methods; unidimensional method; CADCAM; Computer aided manufacturing; Current measurement; Lesions; Medical treatment; Neoplasms; Performance evaluation; Size measurement; Time measurement; Volume measurement; diagnosis; response to therapy; volumetric measurements;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-3931-7
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2009.5192989
