DocumentCode
280340
Title
Inductive protein structure analysis (IPSA)
Author
Schulze-Kremer, Steffen
Author_Institution
Brainware GmbH, Berlin, West Germany
fYear
1990
fDate
33147
Firstpage
42705
Lastpage
42711
Abstract
The current state of protein structure analysis and prediction methods shows three important points. First, classical methods of secondary structure prediction cannot solve the protein folding problem; secondly, a combination of classical method returns better results for the prediction of secondary structures than any one of the methods on its own; and thirdly, methods that try to incorporate the effects of long-range interactions produce a better set of results than comparable methods not using this information. This is the starting point and motivation for a new method of computer-assisted protein structure analysis. The name `Inductive Protein Structure Analysis (IPSA)´ indicates the crux of the method, which is the automated search for patterns and structural regularities at different levels of the structure of proteins. The concept of `induction´ generally describes the process by which a rule is derived from a set of examples
Keywords
biocybernetics; proteins; IPSA; automated search; computer-assisted protein structure analysis; induction; prediction methods; protein folding; protein structure analysis;
fLanguage
English
Publisher
iet
Conference_Titel
Symbols Versus Neurons, IEE Colloquium on
Conference_Location
London
Type
conf
Filename
190574
Link To Document