Title :
Preparation of diclofop-methyl enantiomers by a semi-preparative high-performance liquid chromatography
Author :
Jin, Lixia ; Gao, Weiliang ; Lin, Chunmian ; Zhang, Datong
Author_Institution :
Coll. of Biol. & Environ. Eng., Zhejiang Univ. of Technol., Hangzhou, China
Abstract :
A chiral stationary phase (CSP) was prepared by coating cellulose tris(4-methylbenzoate) (CTMB) onto aminopropylated silica gel. Chiral herbicide diclofop-methyl (DM) was well resolved on analytical coated-CTMB CSP using 85/15 n-hexane/isopropanol as the mobile phase by high-performance liquid chromatography (HPLC), and the semi-preparation of DM enantiomers was conducted by the semi-chromatography. With a concentration 10000 ppm and a 20 μL loop, the yields of (+)-DM and (-)-DM were 1.590 mg/h and 1.583 mg/h, respectively.
Keywords :
chromatography; coatings; gels; isomerism; organic compounds; aminopropylated silica gel; cellulose tris(4-methylbenzoate); chiral herbicide diclofop-methyl; chiral stationary phase; diclofop-methyl enantiomers; semipreparative high-performance liquid atography; Biology; Chemicals; Coatings; Delta modulation; Manuals; Regulators; Silicon compounds; Cellulose tris(4-methylbenzoate); chiral separation; diclofop-methyl; semi-preparation;
Conference_Titel :
Mechanic Automation and Control Engineering (MACE), 2011 Second International Conference on
Conference_Location :
Hohhot
Print_ISBN :
978-1-4244-9436-1
DOI :
10.1109/MACE.2011.5987698
