DocumentCode
2808009
Title
Automatic markup of neural cell membranes using boosted decision stumps
Author
Venkataraju, Kannan Umadevi ; Paiva, Antonio R C ; Jurrus, Elizabeth ; Tasdizen, Tolga
Author_Institution
Sch. of Comput., Univ. of Utah, Salt Lake City, UT, USA
fYear
2009
fDate
June 28 2009-July 1 2009
Firstpage
1039
Lastpage
1042
Abstract
To better understand the central nervous system, neurobiologists need to reconstruct the underlying neural circuitry from electron microscopy images. One of the necessary tasks is to segment the individual neurons. For this purpose, we propose a supervised learning approach to detect the cell membranes. The classifier was trained using AdaBoost, on local and context features. The features were selected to highlight the line characteristics of cell membranes. It is shown that using features from context positions allows for more information to be utilized in the classification. Together with the nonlinear discrimination ability of the AdaBoost classifier, this results in clearly noticeable improvements over previously used methods.
Keywords
biomembranes; cellular biophysics; feature extraction; image classification; image enhancement; image reconstruction; learning (artificial intelligence); medical image processing; neurophysiology; AdaBoost; boosted decision stumps; central nervous system; electron microscopy; image reconstruction; neural cell membranes; neural circuitry; supervised learning; Biomembranes; Cells (biology); Central nervous system; Circuits; Electron microscopy; Image reconstruction; Image segmentation; Machine learning algorithms; Neurons; Transmission electron microscopy; AdaBoost; Machine Learning; Segmentation; Serial-section TEM; cell membrane detection;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on
Conference_Location
Boston, MA
ISSN
1945-7928
Print_ISBN
978-1-4244-3931-7
Electronic_ISBN
1945-7928
Type
conf
DOI
10.1109/ISBI.2009.5193233
Filename
5193233
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