• DocumentCode
    2808009
  • Title

    Automatic markup of neural cell membranes using boosted decision stumps

  • Author

    Venkataraju, Kannan Umadevi ; Paiva, Antonio R C ; Jurrus, Elizabeth ; Tasdizen, Tolga

  • Author_Institution
    Sch. of Comput., Univ. of Utah, Salt Lake City, UT, USA
  • fYear
    2009
  • fDate
    June 28 2009-July 1 2009
  • Firstpage
    1039
  • Lastpage
    1042
  • Abstract
    To better understand the central nervous system, neurobiologists need to reconstruct the underlying neural circuitry from electron microscopy images. One of the necessary tasks is to segment the individual neurons. For this purpose, we propose a supervised learning approach to detect the cell membranes. The classifier was trained using AdaBoost, on local and context features. The features were selected to highlight the line characteristics of cell membranes. It is shown that using features from context positions allows for more information to be utilized in the classification. Together with the nonlinear discrimination ability of the AdaBoost classifier, this results in clearly noticeable improvements over previously used methods.
  • Keywords
    biomembranes; cellular biophysics; feature extraction; image classification; image enhancement; image reconstruction; learning (artificial intelligence); medical image processing; neurophysiology; AdaBoost; boosted decision stumps; central nervous system; electron microscopy; image reconstruction; neural cell membranes; neural circuitry; supervised learning; Biomembranes; Cells (biology); Central nervous system; Circuits; Electron microscopy; Image reconstruction; Image segmentation; Machine learning algorithms; Neurons; Transmission electron microscopy; AdaBoost; Machine Learning; Segmentation; Serial-section TEM; cell membrane detection;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on
  • Conference_Location
    Boston, MA
  • ISSN
    1945-7928
  • Print_ISBN
    978-1-4244-3931-7
  • Electronic_ISBN
    1945-7928
  • Type

    conf

  • DOI
    10.1109/ISBI.2009.5193233
  • Filename
    5193233