Correction of Doppler spectrum widening due to scintillation of decaying microbubble contrast agent injected in flowing fluid, mathematical modeling and in-vitro study

When using microballoon/microbubble contrast agents in a Doppler study, it has been known that there may be an unexplainable Doppler spectrum widening. The study presented here explains the physical background of the phenomena with in-vitro experimental data and tries to establish a way to prevent one from possible misdiagnosis under such a condition. The artifact may be computationally corrected when a certain set of conditions is met