DocumentCode :
2817553
Title :
Quantitative comparison of 3D and 2D PET with brain studies
Author :
Sossi, V. ; Oakes, T.R. ; Chan, G. ; Ruth, T.J.
Author_Institution :
TRIUMF, Vancouver, BC, Canada
Volume :
2
fYear :
1997
fDate :
9-15 Nov 1997
Firstpage :
1438
Abstract :
The statistical superiority of 3D PET compared to 2D PET for brain neuroreceptor and 18-F-fluorodeoxyglucose (FDG) scanning is accepted. However, further validation of the quantitative aspects of data acquired in 3D mode is necessary. A 3D data processing protocol that involves iterative convolution subtraction scatter correction, detector normalization including axial and radial geometric factors, attenuation correction extracted from a 2D transmission scan, the Kinahan-Rogers reconstruction algorithm and region-of-interest based calibration factors was tested on 3D data from eleven human subjects using 11 Cd-hydrotetrabenazine, 11C-Schering 23390 and FDG as tracers, 2D scans were performed on the same subjects and the DV, DVR and LMRGlu values obtained from these were used as reference. The comparison showed good quantitative agreement between the two acquisition modes
Keywords :
brain; calibration; image reconstruction; iterative methods; medical image processing; positron emission tomography; 18-F-fluorodeoxyglucose scanning; 2D PET; 2D transmission scan; 3D PET; C; F; Kinahan-Rogers reconstruction algorithm; attenuation correction; axial geometric factors; brain neuroreceptor scanning; detector normalization; iterative convolution subtraction scatter correction; medical diagnostic imaging; nuclear medicine; radial geometric factors; region-of-interest based calibration factors; Attenuation; Calibration; Convolution; Data mining; Data processing; Detectors; Positron emission tomography; Protocols; Reconstruction algorithms; Scattering;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium, 1997. IEEE
Conference_Location :
Albuquerque, NM
ISSN :
1082-3654
Print_ISBN :
0-7803-4258-5
Type :
conf
DOI :
10.1109/NSSMIC.1997.670590
Filename :
670590
Link To Document :
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