Title :
Mechanism of heart-rate turbulence
Author :
Mrowka, R. ; Persson, PB ; Theres, H. ; Patzak, A.
Author_Institution :
Klink fur Innere Medizin, Humboldt-Univ., Berlin, Germany
Abstract :
Recently, two post-myocardial-infarction risk predictors were introduced that are superior to all other presently available indicators: turbulence onset (TO) and turbulence slope (TS). These new parameters characterize the behavior of instantaneous heart rate after a ventricular premature beat (VPB), i.e., they describe the reestablishing of heart rate control after an acute perturbation. We propose that the dysfunction of an important cardiovascular control mechanism-the arterial baroreflex-is the mechanism behind these new potent markers. The hypothesis is tested by means of a mathematical model. The results of the model indicates that the recently established risk parameters TO and TS characterize baroreflex function, a known risk stratifier in patients
Keywords :
biocontrol; bioelectric potentials; cardiovascular system; haemodynamics; neurophysiology; patient monitoring; physiological models; acute perturbation; arterial baroreflex; baroreflex function; cardiovascular control mechanism; dysfunction; heart rate control; heart-rate turbulence; instantaneous heart rate; mathematical model; patients; post-myocardial-infarction risk predictors; risk parameters; risk stratifier; turbulence onset; turbulence slope; ventricular premature beat; Baroreflex; Cardiology; Frequency; Heart rate; Heart rate variability; Hemodynamics; Mathematical model; Oscillators; Pacemakers; Rhythm;
Conference_Titel :
Computers in Cardiology 2000
Conference_Location :
Cambridge, MA
Print_ISBN :
0-7803-6557-7
DOI :
10.1109/CIC.2000.898553
