Title :
Modeling the Immune Response to HBV Infection
Author :
Changjiang Long ; Anlian Qu ; Huan Qi ; Sheng-He Huang
Author_Institution :
Coll. of Eng. & Technol., Huazhong Agric. Univ., Wuhan, China
Abstract :
A mathematical model describing the immune response to HBV infection was established. The immune reaction effect included both humoral and cellular immune response. Why the immune system failed to eliminate the virus was explained by the equilibrium state analysis result that the immune response was not strong enough to resolve the HBV infection. Simulations were made to show the wide variety of clinical manifestations of HBV infection.
Keywords :
diseases; microorganisms; HBV infection; cellular immune response; equilibrium state analysis; humoral immune response; immune reaction; immune response modeling; immune system; mathematical model; virus; Agricultural engineering; Biological system modeling; Blood; Cells (biology); Educational institutions; Human immunodeficiency virus; Immune system; Liver diseases; Mathematical model; Pathogens;
Conference_Titel :
Computational Intelligence and Software Engineering, 2009. CiSE 2009. International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-4507-3
DOI :
10.1109/CISE.2009.5364085