Systems biology and control — A tutorial

In this tutorial the author introduce some of the concepts that frequently appear at the intersection of control theory and systems biology. Mustafa Khammash and Brian Munsky outline some of the key approaches for the modeling and analysis on cellular noise and the resulting fluctuations in the copy numbers of cellular constituents. Eduardo Sontagintroduces some tools for analyzing deterministic biochemical reaction networks. Pablo Iglesias looks at models of spatially varying chemical reactions, and in particular, how gradients and patterns are formed in cells. Finally, Domitilla Del Vecchio considers important control-theoretic problems in synthetic biology - that is, the synthesis of basic circuits inside cells using genetic regulatory components.