DocumentCode :
285047
Title :
Distance matrices and modified cyclic projections for molecular conformation
Author :
Potter, Lec C. ; Chiang, DaMing
Author_Institution :
Dept. of Electr. Eng., Ohio State Univ., Columbus, OH, USA
Volume :
4
fYear :
1992
fDate :
23-26 Mar 1992
Firstpage :
173
Abstract :
Biological compounds exhibit extraordinary functional specificity as a consequence of their precise spatial structure. Two signal recovery algorithms for computing molecular structure from noisy measurements of interatomic distances are presented. The problem is formulated as the minimization of a quadratic cost over the intersection of constraint sets. In a broader signal recovery context, a technique is utilized for iteratively computing the unique projection onto an intersection of closed convex sets, and the simplification possible with an appropriate choice of norm, despite a nonconvex constraint set, is illustrated
Keywords :
matrix algebra; molecular configurations; set theory; signal processing; biological compounds; closed convex sets; constraint sets; distance matrices; interatomic distances; intersection; modified cyclic projections; molecular conformation; molecular structure; noisy measurements; nonconvex constraint set; quadratic cost minimisation; signal recovery algorithms; spatial structure; Atomic measurements; Biology computing; Bonding; Chemicals; Computational Intelligence Society; Costs; Distance measurement; Euclidean distance; Iterative algorithms; Nuclear magnetic resonance;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Acoustics, Speech, and Signal Processing, 1992. ICASSP-92., 1992 IEEE International Conference on
Conference_Location :
San Francisco, CA
ISSN :
1520-6149
Print_ISBN :
0-7803-0532-9
Type :
conf
DOI :
10.1109/ICASSP.1992.226458
Filename :
226458
Link To Document :
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