DocumentCode
2852339
Title
A quenched oscillator network for pattern formation in gene expression
Author
Hsia, J. ; Holtz, W.A. ; Huang, D.C. ; Arcak, M. ; Maharbiz, M.M.
Author_Institution
Dept. of Electr. Eng. & Comput. Sci., Univ. of California, Berkeley, CA, USA
fYear
2011
fDate
June 29 2011-July 1 2011
Firstpage
2284
Lastpage
2289
Abstract
Biologists have long searched for reaction net works that can spontaneously generate spatial patterns in the presence of diffusion. The studies so far closely follow Alan Turing\´s "activator-inhibitor" model, where diffusion destabilizes a spatially homogeneous steady state. In this paper, we propose a new type of Turing system based on an oscillator that destabilizes a spatially homogeneous steady state towards a spatio-temporal pattern. We develop a model based on current experimentally-viable systems and study its benefits and limitations.
Keywords
Turing machines; genetics; oscillators; spatiotemporal phenomena; activator-inhibitor model; experimentally-viable systems; gene expression; homogeneous steady state; quenched oscillator network; reaction networks; spatio-temporal pattern; turing system; Additives; Eigenvalues and eigenfunctions; Feedback loop; Jacobian matrices; Oscillators; Pattern formation; Steady-state;
fLanguage
English
Publisher
ieee
Conference_Titel
American Control Conference (ACC), 2011
Conference_Location
San Francisco, CA
ISSN
0743-1619
Print_ISBN
978-1-4577-0080-4
Type
conf
DOI
10.1109/ACC.2011.5991116
Filename
5991116
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