DocumentCode :
2852339
Title :
A quenched oscillator network for pattern formation in gene expression
Author :
Hsia, J. ; Holtz, W.A. ; Huang, D.C. ; Arcak, M. ; Maharbiz, M.M.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Univ. of California, Berkeley, CA, USA
fYear :
2011
fDate :
June 29 2011-July 1 2011
Firstpage :
2284
Lastpage :
2289
Abstract :
Biologists have long searched for reaction net works that can spontaneously generate spatial patterns in the presence of diffusion. The studies so far closely follow Alan Turing\´s "activator-inhibitor" model, where diffusion destabilizes a spatially homogeneous steady state. In this paper, we propose a new type of Turing system based on an oscillator that destabilizes a spatially homogeneous steady state towards a spatio-temporal pattern. We develop a model based on current experimentally-viable systems and study its benefits and limitations.
Keywords :
Turing machines; genetics; oscillators; spatiotemporal phenomena; activator-inhibitor model; experimentally-viable systems; gene expression; homogeneous steady state; quenched oscillator network; reaction networks; spatio-temporal pattern; turing system; Additives; Eigenvalues and eigenfunctions; Feedback loop; Jacobian matrices; Oscillators; Pattern formation; Steady-state;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
American Control Conference (ACC), 2011
Conference_Location :
San Francisco, CA
ISSN :
0743-1619
Print_ISBN :
978-1-4577-0080-4
Type :
conf
DOI :
10.1109/ACC.2011.5991116
Filename :
5991116
Link To Document :
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