Anatomy-based dose optimization for HDR-brachytherapy of the prostate using fast simulated annealing algorithm

Author

Lessard, Etienne ; Pouliot, Jean

Volume

4

fYear

2000

fDate

2000

Firstpage

2774

Abstract

The goal of this work is to correctly and completely take into account the anatomical information in the treatment planning of prostate cancer for high dose rate brachytherapy. By using fast simulated annealing algorithm to govern an inverse planning optimization, a highly conformal dose coverage to the target volume is obtained while minimizing urinary and rectal morbidity. Preliminary results show that the authors´ fast simulated annealing algorithm can obtain a highly conformal dose to the prostate while preserving urethra and rectum wall within 15 to 20 minutes of cpu time

Keywords

biological organs; dosimetry; radiation therapy; simulated annealing; 15 to 20 min; HDR-brachytherapy; anatomical information; anatomy-based dose optimization; cpu time; fast simulated annealing algorithm; high dose rate brachytherapy; highly conformal dose coverage; inverse planning; prostate cancer treatment planning; rectal morbidity; rectum wall preservation; target volume; therapeutic nuclear medicine; urethra preservation; urinary morbidity; Anatomy; Applicators; Biomedical applications of radiation; Brachytherapy; Catheters; Implants; Intensity modulation; Prostate cancer; Shape; Simulated annealing;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-6465-1

Type

conf

DOI

10.1109/IEMBS.2000.901437

Filename

901437