Large diameter TiO2 nanotube fabrication for bone morphogenetic protein delivery

Author

Liang, Kun ; Li, Xiaocheng ; Tay, Beng Kang

Author_Institution

Sch. of EEE, Nanyang Technol. Univ., Singapore, Singapore

fYear

2011

fDate

21-24 June 2011

Firstpage

1

Lastpage

2

Abstract

A localized and release controlled carrier is essential to enhance the effectiveness of bone morphogenetic protein (BMP) on bone regeneration and repair. In this work, TiO₂ nanotube will be used for BMP delivery. Different types of TiO₂ nanotubes were successfully fabricated by changing organic electrolyte composition. Large diameter TiO₂ nanotubes were fabricated at high applied potential (550nm at 90V, 680nm at 100V) by use electrolyte for the second time with new substrate. Furthermore, using CNT as template crystallized TiO₂ nanotubes with 300-500nm diameter could also be got with Ti deposition followed by a high temperature annealing. The fabricated large diameter TiO₂ nanotube could be used for protein delivery testing in the future.

Keywords

biomedical engineering; bone; nanotubes; proteins; titanium compounds; TiO₂; bone morphogenetic protein delivery; bone regeneration; bone repair; high temperature annealing; localized controlled carrier; nanotube fabrication; organic electrolyte composition; release controlled carrier; size 300 nm to 500 nm; size 550 nm; size 680 nm; voltage 100 V; voltage 90 V; Bones; Electric potential; Electron tubes; Fabrication; Hafnium; Proteins; Surface topography; TiO2 nanotube; anodization; large diameter;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanoelectronics Conference (INEC), 2011 IEEE 4th International

Conference_Location

Tao-Yuan

ISSN

2159-3523

Print_ISBN

978-1-4577-0379-9

Electronic_ISBN

2159-3523

Type

conf

DOI

10.1109/INEC.2011.5991774

Filename

5991774