Title :
Cellular sorting with femtoliter fluid displacement for integrated flow cytometry systems
Author :
Justis, Nicole B. ; Lien, Victor ; Chen, Randy ; Lo, Yu-Hwa
Author_Institution :
Dept. of Mater. Sci. & Eng., Univ. of California, San Diego, CA
Abstract :
An acousto-optical microfluidic flow cytometer featuring femtoliter fluid-displacement was demonstrated with cellular sorting efficiencies at upwards of 99% at 5 kHz frequency actuation. Simulation and validation was performed using Reynolds stress model for turbulent particle flows.
Keywords :
acousto-optical devices; bioMEMS; biological fluid dynamics; cellular biophysics; integrated optics; micro-optomechanical devices; microfluidics; turbulence; Reynolds stress model; acousto-optical microfluidic flow cytometer; cellular sorting efficiency; femtoliter fluid displacement; integrated flow cytometry systems; turbulent particle flows; Acoustic signal detection; Analytical models; Atmospheric modeling; Biomedical optical imaging; Computational modeling; Frequency; Microfluidics; Optical sensors; Sorting; Ultrafast optics; 120.7250 Velocimetry; 130.3120 Integrated optics devices; 130.6010 Sensors; 170.1470 Blood/tissue constituent monitoring; 170.1530 Cell analysis;
Conference_Titel :
Lasers and Electro-Optics, 2006 and 2006 Quantum Electronics and Laser Science Conference. CLEO/QELS 2006. Conference on
Conference_Location :
Long Beach, CA
Print_ISBN :
978-1-55752-813-1
Electronic_ISBN :
978-1-55752-813-1
DOI :
10.1109/CLEO.2006.4627751
