Title :
Intelligent agent-based modeling of kinesin nanomotor
Author :
Khataee, H.R. ; Aris, T. N Moh ; Sulaiman, M.N. ; Ibrahim, M. Yousef
Author_Institution :
Dept. of Comput. Sci., Univ. Putra Malaysia, Serdang, Malaysia
Abstract :
This paper introduces a new methodology to develop comprehensive structural and behavioral models of kinesin nanomotor within its cell using agent technology. In this work, firstly, kinesin nanomotor is introduced as a physical intelligent agent. Then, we have proposed an agent-based structural model of kinesin nanomotor using composite diagram of Unified Modeling Language (UML). We also introduced its heads and tail as the kinesin´s sensors and its motor domain as its actuator. An agent-based behavioral model of kinesin nanomotor was developed using Finite State Machine (FSM) diagram of UML and illustrated the internal intelligent and autonomous decision-making process of the nanomotor. The proposed agent-based behavioral FSM model was verified with its mathematical definitions which developed as Deterministic Finite Automaton (DFA) and its respective grammar. The outputs of the proposed grammar were in agreement with the proposed DFA model and traced the behavior of the nanomotor in nature. Also, the behavioral DFA model of the nanomotor was implemented as its software agent model. The proposed agent-based structural and behavioral models of kinesin nanomotor introduced the nanomotor as bio-nanoagent which was able to sense its cell through its sensors, make decision internally, and perform actions upon the cell through its actuator.
Keywords :
Unified Modeling Language; biological techniques; biology computing; biosensors; cellular biophysics; decision making; deterministic automata; finite state machines; molecular biophysics; nanosensors; proteins; software agents; UML; Unified Modeling Language; actuator; agent-based behavioral FSM model; agent-based structural model; autonomous decision-making process; behavioral DFA model; bionanoagent; cell; composite diagram; comprehensive structural model; deterministic finite automaton; finite state machine diagram; grammar; intelligent agent-based modeling; kinesin nanomotor; kinesin sensors; motor domain; physical intelligent agent; software agent model; Actuators; Biological system modeling; Computational modeling; Doped fiber amplifiers; Mathematical model; Sensors; Unified modeling language;
Conference_Titel :
IECON 2011 - 37th Annual Conference on IEEE Industrial Electronics Society
Conference_Location :
Melbourne, VIC
Print_ISBN :
978-1-61284-969-0
DOI :
10.1109/IECON.2011.6119310