DocumentCode
2877547
Title
Optical biopsy of liver fibrosis using multiphoton microscopy
Author
Liu, Yuan ; Lee, Hsuan-Shu ; Chen, Hsiao-Ching ; Chiou, Ling-Ling ; Huang, Guan-Tam ; Lo, Wen ; Dong, Chen-Yuan
Author_Institution
Dept. of Phys., Nat. Taiwan Univ., Taipei, Taiwan
fYear
2004
fDate
14-17 Dec. 2004
Firstpage
78
Lastpage
79
Abstract
In this work, we apply multiphoton microscopy in diagnosing toxin (CCl4) induced liver fibrosis in mice. We found that multiphoton induced spectroscopic signatures may be used to identify stellate cell proliferation and necrotic sites. Our study suggests that multiphoton imaging may be developed into an effective diagnosis tool for liver fibrosis in vivo.
Keywords
biomedical optical imaging; carbon compounds; diseases; drugs; liver; multiphoton processes; optical microscopy; CCl4; multiphoton induced spectroscopic signature; multiphoton microscopy; necrotic site; optical biopsy; stellate cell proliferation; toxin induced liver fibrosis; Biomedical imaging; Biomedical optical imaging; Biopsy; Fluorescence; In vivo; Liver; Mice; Optical imaging; Optical microscopy; Optical polarization;
fLanguage
English
Publisher
ieee
Conference_Titel
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN
0-7803-8676-0
Type
conf
DOI
10.1109/APBP.2004.1412287
Filename
1412287
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