Title :
Cell death mechanism in human epidermoid carcinoma A431 cells triggered by photodynamic therapy with Photofrin®
Author :
Hsieh, Ya-Ju ; Wu, Chih-Ching ; Chang, Cheng-Jen ; Yu, Jau-Song
Author_Institution :
Dept. of Cell & Molecular Biol., Chang Gung Univ., Tao-Yuan, Taiwan
Abstract :
Photofrin® distributes dynamically in A431 cells; the plasma membranes and Golgi complex are the main target sites of Photofrin® after a brief (3 h) and prolonged (24 h) incubation, respectively. Cells with differentially localized Photofrin® displayed distinct death phenotypes in response to PDT.
Keywords :
biomembranes; cancer; cellular biophysics; drugs; laser applications in medicine; photodynamic therapy; tumours; 24 h; 3 h; A431 cells; Golgi complex; PDT; Photofrin®; cell death mechanism; human epidermoid carcinoma; photodynamic therapy; plasma membranes; Biology; Biomembranes; Cells (biology); Glass; Humans; Medical treatment; Microscopy; Morphology; Plasma displays; Protocols;
Conference_Titel :
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN :
0-7803-8676-0
DOI :
10.1109/APBP.2004.1412291