DocumentCode
2878904
Title
A micromanipulation platform based on magnetic tweezers and total internal reflection fluorescence microscopy for cell mechanical studies
Author
Lee, Chaug-Chun ; Chien, Cheng-Hao ; Wen, Liang-Kung ; Dong, Chen-Yuan
Author_Institution
Dept. of Phys., Nat. Taiwan Univ., Taipei, Taiwan
fYear
2004
fDate
14-17 Dec. 2004
Firstpage
199
Lastpage
200
Abstract
We developed a manipulation platform, which combines magnetic tweezers and the incubating system, with total internal reflection fluorescence microscopy (TIRFM). Our system can generate forces up to the nN range and such forces can be used to observe and characterize cell mechanical responses to external forces. Combined with TIRFM, cell surface stress-strain phenomena can also be investigated.
Keywords
biomechanics; cell motility; fluorescence; micromanipulators; optical microscopy; cell mechanical study; cell surface stress-strain phenomena; fluorescence microscopy; magnetic tweezers; micromanipulation platform; total internal reflection; Biomembranes; Biophysics; Cells (biology); Fluorescence; Force control; Instruments; Laboratories; Magnetic force microscopy; Physics; Reflection;
fLanguage
English
Publisher
ieee
Conference_Titel
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN
0-7803-8676-0
Type
conf
DOI
10.1109/APBP.2004.1412350
Filename
1412350
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