Title :
Backpropagation learning on ribosomal binding sites in DNA sequences using preprocessed features
Author :
Pratt, Lorien Y. ; Tracy, Lauren L. ; Noordewier, Michiel
Author_Institution :
Dept. of Math. & Comput. Sci., Colorado Sch. of Mines, Golden, CO, USA
fDate :
27 Jun-2 Jul 1994
Abstract :
Several studies have explored how neural networks can be used to find genes within regions of previously uncharacterized deoxyribonucleic acid (DNA). This paper describes the creation of a neural network training set for determining which part of a DNA strand codes for an important genetic feature called a ribosomal binding site (RBS). Based on previous research on detecting other genetic features, this data set contains preprocessed features that reflect biologically meaningful patterns in the raw base pair [ACTG]* language. We also describe preliminary empirical results indicating neural network performance that is superior to all other automated methods for detecting RBS´s
Keywords :
DNA; biology computing; feature extraction; genetics; learning (artificial intelligence); neural nets; pattern classification; DNA sequences; RBS extraction; backpropagation learning; genetic feature; neural networks; ribosomal binding sites; strand codes; Backpropagation; Biological information theory; Cells (biology); DNA; Genetics; Laboratories; Neural networks; Organisms; Proteins; Sequences;
Conference_Titel :
Neural Networks, 1994. IEEE World Congress on Computational Intelligence., 1994 IEEE International Conference on
Conference_Location :
Orlando, FL
Print_ISBN :
0-7803-1901-X
DOI :
10.1109/ICNN.1994.374790