Mutagenesis induced by XeCl laser radiation

Author

Belloni, F. ; Alifano, P. ; Doria, D. ; Lorusso, A. ; Monaco, C. ; Nassisi, V. ; Tala, A. ; Tredici, M.

Author_Institution

Dept. of Phys., Lecce Univ.

fYear

2005

fDate

17-17 June 2005

Firstpage

638

Lastpage

638

Abstract

In this work the mutagenic effect on Escherichia coli strains of UV radiation emitted by a XeCI laser (lambda=308 nm, tau=20 ns, 100 mJ pulse energy) has been analyzed as a function of the exposure dose and compared with the effect induced by 254 nm radiation emitted by a conventional germicidal lamp. Mutations can involve any genome site and therefore can give rise to various phenotypes, which then can be suitably selected. As a consequence, the impact of the induced mutagenesis is outstanding, both in scientific and industrial fields. In particular suitable doses of UV radiation can induce mutations, while higher doses can cause cell death, due to the induction of manifold damages to DNA

Keywords

DNA; biological effects of laser radiation; cellular biophysics; excimer lasers; genetics; microorganisms; molecular biophysics; 100 mJ; 20 ns; 308 nm; DNA; Escherichia coli; UV radiation emitted; XeCI laser; XeCl; cell death; conventional germicidal lamp; genome site; mutagenic effect; phenotypes; Bioinformatics; Capacitive sensors; DNA; Genetic mutations; Genomics; Industrial accidents; Lamps; Laser theory; Microorganisms; Optical pulses;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics Europe, 2005. CLEO/Europe. 2005 Conference on

Conference_Location

Munich

Print_ISBN

0-7803-8974-3

Type

conf

DOI

10.1109/CLEOE.2005.1568414

Filename

1568414