Title :
Evaluation of the TierPET system
Author :
Weber, S. ; Herzog, H. ; Coenen, H.H. ; Cremer, M. ; Engels, R. ; Hamacher, K. ; Kehren, F. ; Muehlensiepen, H. ; Ploux, L. ; Reinartz, R. ; Reinhart, P. ; Rongen, F. ; Sonnenberg, F. ; Halling, H.
Author_Institution :
Forschungszentrum Julich GmbH, Germany
Abstract :
The TierPET system, a high resolution 3D positron emission tomograph, has been developed to perform small animal positron emission tomography (PET) studies. High resolution PET opens the possibility to perform animal trials without the need for vivisection. This reduces the expense for such experiments, saving animal lives and cutting costs for example for the development of new radiopharmaceuticals. The scanner uses two orthogonal pairs of detectors consisting of arrays of small individual YAP crystals coupled to position sensitive photomultipliers. The detector-to-detector distance may be varied to improve either sensitivity or spatial resolution. The spatial resolution of the scanner is 2.1 mm
Keywords :
biomedical equipment; image resolution; positron emission tomography; 2.1 mm; TierPET system evaluation; YAP; YAlO3; animal lives saving; cutting costs; high resolution PET; medical instrumentation; new radiopharmaceuticals development; small animal positron emission tomography studies; vivisection; Aluminum; Animals; Crystals; Detectors; Drugs; Optical scattering; Photomultipliers; Positron emission tomography; Spatial resolution; Transmission line matrix methods;
Conference_Titel :
Nuclear Science Symposium, 1998. Conference Record. 1998 IEEE
Conference_Location :
Toronto, Ont.
Print_ISBN :
0-7803-5021-9
DOI :
10.1109/NSSMIC.1998.773827