Title :
Highly parallel integrated microfluidic biochannel arrays
Author :
Liu, R.H. ; Chen, H. ; Luehrsen, K.R. ; Ganser, D. ; Weston, D. ; Blackwell, J. ; Grodzinski, P.
Author_Institution :
Lab. of Microfluidics, Motorola Labs., Tempe, AZ, USA
Abstract :
Microfluidic biochannel arrays that integrates massively parallel microfluidic channels with Motorola glass-based microarray biochips have been successfully developed. We demonstrated that such a device allows DNA hybridization assays to be performed in a miniaturized and highly parallel fashion. The biochannel arrays are a new DNA diagnostics platform that has several desirable features such as single-use and cost-effective, highly parallel (up to 52 protocols in parallel), and processed rapidly. Additionally, only nanoliter-volumes (/spl sim/100 nL) of DNA sample/reagents are consumed per array.
Keywords :
DNA; biological techniques; microfluidics; DNA hybridization assay; Motorola glass microarray biochip; genetic analysis; massively parallel microfluidic channels; microfluidic biochannel array; Costs; DNA; Diseases; Genetics; Glass; Microchannel; Microfluidics; Performance analysis; Probes; Testing;
Conference_Titel :
Micro Electro Mechanical Systems, 2001. MEMS 2001. The 14th IEEE International Conference on
Conference_Location :
Interlaken, Switzerland
Print_ISBN :
0-7803-5998-4
DOI :
10.1109/MEMSYS.2001.906572
