Experimental characterization of nanoscale optofluidic sensor arrays

The potential for associating panels of biomarkers with disease states and the need to rapidly diagnose pathogenic threats requires the development of new biosensor technologies which can combine the multiplexing capabilities of traditional microarrays with the sensitivity of emerging nanosensors. In this paper we introduce our Nanoscale Optofluidic Sensors Arrays which combine the advantages of both these approaches. In this paper we describe the operating principal of the array and the fabrication, integration and functionalization techniques involved in creating it. Initial characterization experiments are presented demonstrating the bulk sensitivity of the array and the independence of each sensor element.