Addressable fluidic gate arrays for layer-to-layer parallel fluidic transportation system

This paper presents addressable fluidic gate arrays for layer to layer parallel fluidic transportation system. Various valve systems for switching of in-plane fluidic network are studied in muTAS. Presented addressable fluidic gate is composed of double-valves driven by pneumatic pressure. One of the double-valves is controlled by row channel and the other is controlled by column channel for row/column addressing. Our study applies addressable fluidic gate arrays to layer to layer transportation beyond in-plane fluidic network system. The layer to layer transportation makes it possible to collect targeted samples from a testing well plate. 3 x 3 fluidic gate arrays based on the presented concept will be demonstrated. Demonstrated fluidic system is based on all PDMS structures. Technically, this paper also reports a dome shape chamber for high sealing and a switching valve having bi-stable diaphragm for memory function.