Title :
Reconstructing grasping motions from high-frequency local field potentials in primary motor cortex
Author :
Zhuang, Jun ; Truccolo, Wilson ; Vargas-Irwin, Carlos ; Donoghue, John P.
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
Recent developments in neural interface systems hold the promise to restore movement in people with paralysis. In search of neural signals for control of neural interface systems, previous studies have investigated primarily single and multiunit activity, as well as low frequency local field potentials (LFPs). In this paper, we investigate the information content about grasping motion of a broad band high frequency LFP (200 Hz - 400 Hz) by classifying discrete grasp aperture states and decoding continuous aperture trajectories. LFPs were recorded via 96-microelectrode arrays in the primary motor cortex (M1) of two monkeys performing free 3-D reaching and grasping towards moving objects. Our results indicate that broad band high frequency LFPs could serve as useful signals for restoring a motor function such as grasp control.
Keywords :
bioelectric potentials; biomedical measurement; neuromuscular stimulation; broadband high frequency LFP local field potential; continuous aperture trajectory decoding; discrete grasp aperture state; frequency 200 Hz to 400 Hz; grasping motion reconstruction; high frequency local field potential; low frequency local field potentials; microelectrode arrays; neural interface system control; neural interface systems; neural signals; paralysed person movement restoration; primary motor cortex; Apertures; Decoding; Grasping; Kalman filters; Kinematics; Support vector machines; Trajectory; Action Potentials; Animals; Hand Strength; Macaca mulatta; Male; Motor Cortex;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5626228
