Dermatological Investigation by Three-Dimensional Line-Field Fourier Domain Optical Coherence Tomography

Three-dimensional optical coherence tomography using only one-dimensional mechanical scanning is demonstrated. This system uses the principle of Fourier domain optical coherence tomography for depth resolution, one-dimensional imaging for lateral vertical resolution, and mechanical scanning by a galvanometer for lateral horizontal resolution. An in vivo human fingerpad is investigated three-dimensionally. The acquisition time for a single cross section is 1 ms and that for a single volume is 10 s, and the system sensitivity is 75.6 dB.