Title :
A control theoretic approach to venom immunotherapy with state jumps
Author :
Chang, H. ; Astolfi, A. ; Shim, H.
Author_Institution :
Dept. of Electr. & Electron. Eng., Imperial Coll. London, London, UK
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
We investigate a model-based control method to boost the immune response. We apply this control method to select the appropriate immune response between the Th1 and Th2 responses. The idea of state jump is discussed using hybrid models notation. To implement the control idea we propose physically available methods.
Keywords :
closed loop systems; control theory; diseases; microorganisms; open loop systems; patient treatment; Th1 response; Th2 response; bee venom immunotherapy; control theory; hybrid models notation; immune response boosting; model based control method; state jumps; venom immunotherapy; Acquired immune deficiency syndrome; Biological system modeling; Control systems; Human immunodeficiency virus; Immune system; Pathogens; Animals; Bee Venoms; Bees; Computer Simulation; Desensitization, Immunologic; Humans; Hypersensitivity; Immunotherapy; Insect Bites and Stings; Models, Immunological; Therapy, Computer-Assisted;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5626304
