Title :
Interactions among MARM binding factors
Author :
Das, Biswajit ; Majumder, D.
Author_Institution :
Dept. of Physiol., West Bengal State Univ., Kolkata, India
fDate :
Oct. 30 2012-Nov. 2 2012
Abstract :
Various transcription factors (TFs) bind to the specific region in the promoter region of the major histocompatibility complex (MHC), thereby regulate the expression of MHC. These TFs are associated with different disease cases in human. Due to unavailability of structural information regarding these TFs it is not yet possible to reveals the molecular interaction mechanism among them. Using of bioinformatics approach like 3D protein structure prediction, molecular dynamics and molecular docking, we hypothesize the molecular rationale regarding the molecular interactions among them.
Keywords :
bioinformatics; diseases; molecular biophysics; molecular configurations; molecular dynamics method; proteins; 3D protein structure prediction; MARM binding factor interactions; bioinformatics; human disease cases; major histocompatibility complex; molecular docking; molecular dynamics; molecular interaction mechanism; molecular rationale; structural information; transcription factors; Communications technology; Decision support systems; MARM; MHC regulation; molecular docking; molecular modeling; transcription factor;
Conference_Titel :
Information and Communication Technologies (WICT), 2012 World Congress on
Conference_Location :
Trivandrum
Print_ISBN :
978-1-4673-4806-5
DOI :
10.1109/WICT.2012.6409073
