DocumentCode :
2925946
Title :
Spike detection in extracellular recordings by hybrid blind beamforming
Author :
Natora, Michal ; Franke, Felix ; Obermayer, Klaus
Author_Institution :
Inst. for Software Eng. & Theor. Comput. Sci., Berlin Inst. of Technol., Berlin, Germany
fYear :
2010
fDate :
Aug. 31 2010-Sept. 4 2010
Firstpage :
4636
Lastpage :
4641
Abstract :
In the case of extracellular recordings, spike detection algorithms are necessary in order to retrieve information about neuronal activity form the data. We present a new spike detection algorithm which is based on methods from the field of blind equalization and beamforming. In contrast to existing approaches, our method estimates several waveforms directly from the data and corresponding linear filters are constructed. The estimation is done in an unsupervised manner, and the few parameters of the algorithm are intuitive to set. The algorithm allows for superior detection performance, even when multiple neurons with various waveforms are present in the data. We compare our method with current state-of-the-art spike detection algorithms, and show that the proposed method achieves favorable results.
Keywords :
blind equalisers; cellular biophysics; medical signal detection; neurophysiology; parameter estimation; blind equalization; extracellular recordings; hybrid blind beamforming; linear filters; neuronal activity; spike detection; Blind equalizers; Detection algorithms; Estimation; Kernel; Neurons; Signal to noise ratio; Action Potentials; Algorithms; Diagnosis, Computer-Assisted; Electrodiagnosis; Humans; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
ISSN :
1557-170X
Print_ISBN :
978-1-4244-4123-5
Type :
conf
DOI :
10.1109/IEMBS.2010.5626483
Filename :
5626483
Link To Document :
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