Title :
A new model for diffusion weighted MRI: Complete Fourier direct MRI
Author_Institution :
Biomed. MR Lab., Washington Univ. in St. Louis, St. Louis, MO, USA
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
The diffusion weighted MR signal is modeled using particle methods. The model shows that the signal is the Fourier transform of the distribution function of the number of spins at the initial time at a given position with a given displacement integral value. The distribution function is computed via Fourier transform steps that keep the Hermitian property of the signal in order to guarantee that the distribution function is real valued. The function, which depicts the tissue microstructure `as it is´ without being tied to any expansions, transformations and assumptions such as Markovian property or symmetry about the spin motions, is displayed using isosurfaces overlayed on the spin density map for a fixed baboon brain sample.
Keywords :
Fourier transforms; Markov processes; biological tissues; biomedical MRI; brain; medical image processing; Fourier transform; Markovian property; baboon brain; diffusion weighted MRI; distribution function; isosurfaces; particle methods; spin density map; spin motions; tissue microstructure; Animals; Equations; Fourier transforms; Isosurfaces; Magnetic resonance imaging; Nuclear magnetic resonance; Algorithms; Animals; Brain; Diffusion Magnetic Resonance Imaging; Fourier Analysis; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Markov Chains; Models, Statistical; Papio; Signal Processing, Computer-Assisted;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5626530