DocumentCode
2929457
Title
Silicon nanowires for bioadhesive drug delivery
Author
Fischer, K. ; Tao, Sarah ; Daniels, Hugh ; Li, Edward ; Desai, Tejal
Author_Institution
Univ. of California San Francisco, San Francisco, CA
fYear
2008
fDate
15-17 Dec. 2008
Firstpage
1
Lastpage
4
Abstract
A technique to coat three dimensional surfaces with silicon nanowires was used to create test devices to characterize the adhesion of microspheres to a model of the human intestine with the end goal of increasing bioavailability in drug delivery. Results indicate negligible toxicity and significant improvements in adhesion over conventional technologies.
Keywords
adhesion; coatings; drug delivery systems; elemental semiconductors; silicon; surface treatment; adhesion; bioadhesive drug delivery; bioavailability; human intestine; microspheres; silicon nanowires; three dimensional surfaces; Adhesives; Chemicals; Coatings; Drug delivery; In vitro; Nanowires; Polymers; Silicon; Surface topography; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Electron Devices Meeting, 2008. IEDM 2008. IEEE International
Conference_Location
San Francisco, CA
ISSN
8164-2284
Print_ISBN
978-1-4244-2377-4
Electronic_ISBN
8164-2284
Type
conf
DOI
10.1109/IEDM.2008.4796686
Filename
4796686
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