• DocumentCode
    2929457
  • Title

    Silicon nanowires for bioadhesive drug delivery

  • Author

    Fischer, K. ; Tao, Sarah ; Daniels, Hugh ; Li, Edward ; Desai, Tejal

  • Author_Institution
    Univ. of California San Francisco, San Francisco, CA
  • fYear
    2008
  • fDate
    15-17 Dec. 2008
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    A technique to coat three dimensional surfaces with silicon nanowires was used to create test devices to characterize the adhesion of microspheres to a model of the human intestine with the end goal of increasing bioavailability in drug delivery. Results indicate negligible toxicity and significant improvements in adhesion over conventional technologies.
  • Keywords
    adhesion; coatings; drug delivery systems; elemental semiconductors; silicon; surface treatment; adhesion; bioadhesive drug delivery; bioavailability; human intestine; microspheres; silicon nanowires; three dimensional surfaces; Adhesives; Chemicals; Coatings; Drug delivery; In vitro; Nanowires; Polymers; Silicon; Surface topography; Testing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Electron Devices Meeting, 2008. IEDM 2008. IEEE International
  • Conference_Location
    San Francisco, CA
  • ISSN
    8164-2284
  • Print_ISBN
    978-1-4244-2377-4
  • Electronic_ISBN
    8164-2284
  • Type

    conf

  • DOI
    10.1109/IEDM.2008.4796686
  • Filename
    4796686