Title :
Spontaneous patterning obtained by evaporation of Human Elastin-like Polypeptide solutions
Author :
Bandiera, Antonella ; Urbani, Ranieri ; Sist, Paola
Author_Institution :
Dept., Univ. of Trieste, Trieste, Italy
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
The potential of producing patterned, bioactive coatings with Human Elastin-Like Polypeptides (HELPs) has been investigated. The physicochemical features of these compounds have evidenced some differences between the two recombinantly expressed products. By a device-free, simple route and avoiding the use of chemically unfriendly compounds, micropatterned surfaces with the ability to control cell behavior could be obtained. Thus, HELPs represent a very promising class of macromolecule for future applications in surface engineering.
Keywords :
biochemistry; biomedical materials; cellular biophysics; coatings; evaporation; macromolecules; molecular biophysics; proteins; bioactive coatings; cell behavior; evaporation; human elastin-like polypeptides; macromolecule; micropatterned surfaces; physicochemical features; spontaneous patterning; Coatings; Geometry; Humans; Polymers; Surface morphology; Surface treatment; Binding Sites; Coated Materials, Biocompatible; Desiccation; Elastin; Humans; Materials Testing; Peptides; Protein Binding; Solutions;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5626761
