Title :
A high-voltage, high-current CMOS pulse generator ASIC for deep brain stimulation
Author :
Laotaveerungrueng, Noppasit ; Lahiji, Rosa R. ; Garverick, Steven L. ; Mehregany, Mehran
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Case Western Reserve Univ., Cleveland, OH, USA
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
A high-voltage, high-current pulse generator ASIC based on 0.35-μm high-voltage CMOS technology is presented. The chip has eight independently-controlled biphasic output channels that can generate either current- or voltage-controlled pulses. The output driver is capable of delivering current up to 1.26 mA or 5.04 mA and voltage up to 2.36 V or 9.45 V; all with 6-bit resolution. The stimulation frequency can be adjusted between 3 Hz to 5 kHz, while pulse width can vary from 20 μs to 640 μs in 20 μs steps for 100-kHz clock frequency. The timing parameters can be adjusted further by varying the clock frequency. These parameters, including pulse phase, can be programmed independently in each channel to allow different waveform generation. The foregoing provides an on-chip solution for an arbitrary function generator that can be monolithically fabricated with the rest of the circuitry. Based on its configuration this chip is an ideal solution for deep brain stimulation (DBS) electrode for targeted stimulation through current steering.
Keywords :
CMOS analogue integrated circuits; application specific integrated circuits; biomedical electrodes; biomedical electronics; brain; driver circuits; neuromuscular stimulation; pulse generators; arbitrary function generator; current steering; current-controlled pulses; deep brain stimulation; electrode; frequency 100 kHz; high-voltage CMOS technology; high-voltage high-current pulse generator ASIC; independently-controlled biphasic output channels; output driver; pulse phase; size 0.35 mum; time 20 mus to 650 mus; timing parameters; voltage-controlled pulses; Computer architecture; Driver circuits; Electrodes; Operational amplifiers; Satellite broadcasting; Transistors; Voltage control; Deep Brain Stimulation; Electric Stimulation Therapy; Electrodes, Implanted; Equipment Design; Equipment Failure Analysis; Pattern Recognition, Automated; Signal Processing, Computer-Assisted;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5626836
