DocumentCode :
2933073
Title :
A simple yet effective data integration approach to tree-based microarray data classification
Author :
Liu, Lin ; Li, Yi ; Liu, Bing ; Li, Jiuyong
Author_Institution :
Sch. of Comput. & Inf. Sci., Univ. of South Australia, Mawson Lakes, SA, Australia
fYear :
2010
fDate :
Aug. 31 2010-Sept. 4 2010
Firstpage :
1503
Lastpage :
1506
Abstract :
Different biological labs conduct similar experiments on same diseases. It is highly desirable to have a better model based on more experimental results than that on a single result. In this paper, we propose a method for integrating microarray data from multiple sources for building classification models. To test the method, we use three real world microarray data sets from different labs with different experimental devices and environments. Although microarray data is well known for its inconsistencies across labs, we demonstrate that it is possible to build consistent models using data sets from multiple labs. We report our method, experimental results and observations in the paper.
Keywords :
bioinformatics; cellular biophysics; data analysis; decision trees; genetics; genomics; pattern classification; classification models; data integration; decision tree; gene expression levels; microarray data; random forest; tree-based classification models; Accuracy; Cancer; Classification algorithms; Classification tree analysis; Data models; Joints; Radio frequency; Algorithms; Humans; Information Storage and Retrieval; Lung Neoplasms; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Pattern Recognition, Automated; Systems Integration; Tumor Markers, Biological;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
ISSN :
1557-170X
Print_ISBN :
978-1-4244-4123-5
Type :
conf
DOI :
10.1109/IEMBS.2010.5626842
Filename :
5626842
Link To Document :
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