DocumentCode
2933073
Title
A simple yet effective data integration approach to tree-based microarray data classification
Author
Liu, Lin ; Li, Yi ; Liu, Bing ; Li, Jiuyong
Author_Institution
Sch. of Comput. & Inf. Sci., Univ. of South Australia, Mawson Lakes, SA, Australia
fYear
2010
fDate
Aug. 31 2010-Sept. 4 2010
Firstpage
1503
Lastpage
1506
Abstract
Different biological labs conduct similar experiments on same diseases. It is highly desirable to have a better model based on more experimental results than that on a single result. In this paper, we propose a method for integrating microarray data from multiple sources for building classification models. To test the method, we use three real world microarray data sets from different labs with different experimental devices and environments. Although microarray data is well known for its inconsistencies across labs, we demonstrate that it is possible to build consistent models using data sets from multiple labs. We report our method, experimental results and observations in the paper.
Keywords
bioinformatics; cellular biophysics; data analysis; decision trees; genetics; genomics; pattern classification; classification models; data integration; decision tree; gene expression levels; microarray data; random forest; tree-based classification models; Accuracy; Cancer; Classification algorithms; Classification tree analysis; Data models; Joints; Radio frequency; Algorithms; Humans; Information Storage and Retrieval; Lung Neoplasms; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Pattern Recognition, Automated; Systems Integration; Tumor Markers, Biological;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location
Buenos Aires
ISSN
1557-170X
Print_ISBN
978-1-4244-4123-5
Type
conf
DOI
10.1109/IEMBS.2010.5626842
Filename
5626842
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