Title :
UV laser footprinting and DNA-protein crosslinking
Author :
Angelov, D. ; Dimitrov, S. ; Cadet, J.
Author_Institution :
Inst. of Solid State Phys., Bulgarian Acad. of Sci., Sofia, Bulgaria
Abstract :
Summary form only given. Protein-nucleic acid complexes are the main players of the processes involved in the control of gene expression and regulation. Direct and powerful approaches for studying these interactions are footprinting and protein-DNA crosslinking formation. Protein-DNA crosslinking detects the presence of a protein on a given DNA sequence, while footprinting allows to study the mechanism of protein-DNA interactions.
Keywords :
DNA; biological effects of ultraviolet radiation; biomolecular effects of radiation; molecular biophysics; proteins; DNA sequence; DNA-protein crosslinking; UV laser footprinting; direct approaches; footprinting; gene expression; gene regulation; protein-DNA crosslinking formation; protein-DNA interactions; protein-nucleic acid complexes; DNA; Gratings; Laser beams; Laser transitions; Laser tuning; Light sources; Optical pulse generation; Optical pulses; Power lasers; Proteins;
Conference_Titel :
Quantum Electronics Conference, 2000. Conference Digest. 2000 International
Conference_Location :
Nice, France
Print_ISBN :
0-7803-6318-3
DOI :
10.1109/IQEC.2000.908189
