Title :
Cardiovascular and respiratory dynamics in patients with sleep apnea
Author :
Penzel, Thomas ; Wessel, Niels ; Riedl, Maik ; Kantelhardt, Jan W. ; Glos, Martin ; Fietze, Ingo
Author_Institution :
Charite Center for Cardiology, Charite Univ. Hosp., Berlin, Germany
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
Sleep is an active and regulated process with restorative functions for physical and mental conditions. Based on recordings of brain waves and the analysis of characteristic patterns and waveforms it is possible to distinguish wakefulness and five sleep stages. Sleep and the sleep stages modulate autonomous nervous system functions such as body temperature, respiration, blood pressure, and heart rate. Methods of statistical physics are used to analyze heart rate and respiration to detect changes of the autonomous nervous system during sleep. Detrended fluctuation analysis and synchronization analysis and their applications to heart rate and respiration during sleep in healthy subjects and patients with sleep disorders are presented. The observed changes can be used to distinguish sleep stages in healthy subjects as well as to differentiate normal and disturbed sleep on the basis of heart rate and respiration recordings without direct recording of brain waves. Of special interest are the cardiovascular consequences of disturbed sleep because they present a risk factor for cardiovascular disorders such as arterial hypertension, cardiac ischemia, sudden cardiac death, and stroke.
Keywords :
biomedical measurement; diseases; electrocardiography; haemodynamics; pneumodynamics; sleep; statistical analysis; arterial hypertension; autonomous nervous system functions; blood pressure; body temperature; cardiac ischemia; cardiovascular disorders; cardiovascular dynamics; detrended fluctuation analysis; heart rate; respiration; respiratory dynamics; sleep apnea patients; sleep stages; statistical analysis; stroke; sudden cardiac death; synchronization analysis; wakefulness; Cardiology; Correlation; Fluctuations; Heart rate variability; Sleep apnea; Analysis of Variance; Electrocardiography; Electromyography; Heart Rate; Humans; Respiratory Mechanics; Signal Processing, Computer-Assisted; Sleep Apnea, Obstructive;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5627434