Title :
Response of human coronary arteries at different mechanical conditions
Author_Institution :
Mater. Sci. Dept., Tech. Univ. of Madrid, Madrid, Spain
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
The lack of reliable mechanical data on coronary arteries hampers the application of numerical models to vascular problems, and precludes physicians from knowing in advance the response of coronary arteries to the different interventions. In this work, the mechanical properties of human coronary arteries have been characterized. Whole samples from human right (RC) and left anterior descending (LAD) coronary arteries aged between 23 and 83 years have been studied by means of in-vitro tensile testing up to failure. Knowledge of the mechanical response of human coronary arteries could be applied to optimize the election of vascular grafts or to prevent arterial damage during angioplasty.
Keywords :
biomechanics; blood vessels; cardiovascular system; failure (mechanical); tensile testing; age 23 yr to 83 yr; angioplasty; arterial damage; failure; human coronary arteries; human right coronary artery; in-vitro tensile testing; left anterior descending coronary artery; mechanical conditions; mechanical properties; vascular grafts; vascular problems; Arteries; Elbow; Humans; In vivo; Stress; Testing; Adult; Aged, 80 and over; Aging; Coronary Vessels; Elastic Modulus; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Tensile Strength; Young Adult;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5627456