Title :
Destructive power dynamics of alpha-theta oscillations via spike and wave in CA3
Author :
Dong, Guoya ; Chen, Xiaogang ; Li, Wenwen ; Cheng, Zhishuang ; Ge, Manling
Author_Institution :
Province-Minist. Joint Key Lab. of Electromagn. Field & Electr. Apparatus Reliability, Hebei Univ. of Technol., Tianjin, China
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
The power dynamics of alpha-theta oscillations via inter-ictal spikes and waves (SWs) in CA3 is investigated by means of Hilbert transform and the statistical method based on CA3 channel of LFP(Local Field Potention) data sampled on total 6 rats in resting with sniffing and of iEEG data on total 10 patients in quiet wakefulness. The comparison of alpha-theta power is done between the inter-ictal groups and control groups. It is concluded that the inter-ictal SWs can disrupt the power of alpha-theta oscillations, leading to the decreased power after SW. Because the alpha-theta oscillations are related with the cognition, it is estimated that the inter-ictal SWs can negatively affected the cognitive function during the inter-ictal dynamics, although the alpha-theta power will be recoverable in some days after injections, even exceed over the power level before injections.
Keywords :
Hilbert transforms; bioelectric potentials; cognition; electroencephalography; medical signal processing; statistical analysis; CA3 channel; EEG; Hilbert transform; alpha-theta oscillations; cognitive function; electroencephalogram; inter-ictal spikes; inter-ictal waves; local field potention; power dynamics; quiet wakefulness; statistical method; Bismuth; Cognition; Epilepsy; Humans; Oscillators; Rats; Rhythm; Spike and wave transition; alpha-theta oscillations; cognition; inter-ictal; Alpha Rhythm; Animals; Biomechanics; Biomedical Engineering; CA3 Region, Hippocampal; Cognition; Electroencephalography; Humans; Models, Statistical; Muscarinic Agonists; Oscillometry; Pilocarpine; Rats; Theta Rhythm; Time Factors;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5627496