A method for reducing fouling at the sensor-sample interface

Author

Gregory, C.M. ; Hatfield, J V ; Higgins, S. ; Vadgama, P.J.

Author_Institution

Dept. of Electr. Eng. & Electron., Univ. of Manchester Inst. of Sci. & Technol., UK

Volume

1

fYear

1999

fDate

1999

Firstpage

365

Abstract

A method of reducing fouling/biofouling on the active surface of sensors in unclean environments is presented. The effect exploited in this system depends on differences in the diffusion coefficients of the analytes (or microsolutes) and foulants (or cellular material). Details of the fabrication and testing are given. Results of experiments with a micromachined flow cell are presented and contrasted with those of a computational fluid dynamics model. Modelling shows effective repulsion of foulants and predicts a signal strength consistent with experimental results

Keywords

biological techniques; cellular biophysics; channel flow; computational fluid dynamics; diffusion; electrochemical sensors; active surface; cellular material; computational fluid dynamics; diffusion coefficients; effective repulsion; fabrication; foulants; fouling/biofouling; micromachined flow cell; sensor-sample interface; signal strength; testing; unclean environments; Amperometric sensors; Biochemistry; Biological materials; Biosensors; Blood; Electrodes; Fabrication; Hospitals; Sensor phenomena and characterization; Sensor systems;

fLanguage

English

Publisher

ieee

Conference_Titel

Instrumentation and Measurement Technology Conference, 1999. IMTC/99. Proceedings of the 16th IEEE

Conference_Location

Venice

ISSN

1091-5281

Print_ISBN

0-7803-5276-9

Type

conf

DOI

10.1109/IMTC.1999.776777

Filename

776777